We study the signalling mechanisms cells use to respond to DNA damage and why defects in these...
Title
Research
Research Groups
Cancer Therapeutics and mRNA Dysregulation
Investigating post-transcriptional mechanisms that drive cancer behaviour and researching novel...
Cancer and Immunogenetics Laboratory
Our major interests are in the fundamental genetics and biology of colorectal cancer and their...
Oncological Image Analysis
We develop image analysis methods for quantitative analysis of medical images,...
Nucleic Acids Research Group
We design and synthesise chemically modified DNA for diagnostic and therapeutic applications....
Computational Biology and Integrative Genomics
We use system biology approaches to search for integrated genomic blueprints that enable us to...
Cancer therapeutics, DNA damage and repair laboratory
A major focus of our work is exploring how ATRX prevents normal cells from elongating their...
Radiopharmaceuticals and Molecular Imaging Group
We aim to develop new radioisotope-labelled compounds for the imaging of tumour biology.
Cell Cycle and Ubiquitin Signalling
Our group objective is to understand the role of the ubiquitin system in cancer cell survival...
Biochemistry and Regulation of DNA Repair Group
My interests over the years have focussed on the proteins and mechanisms involved in the...
Genomics of Inflammation and Cancer Immunology
We are interested in the genetic and epigenetic determinants of inter-individual variation in...
Novel Clinical Imaging Research Group
Our group focuses on using imaging techniques in small-scale trials with the particular...
Tumour Hypoxia Group
We are investigating how tumours survive in conditions which include low oxygen (hypoxia). Our...
Hypoxia and Angiogenesis Group
The focus of the group is on tumour angiogenesis and the role of notch signalling, and hypoxia...
New Technical Radiotherapy/Advanced Radiation Oncology Group
Personalising gastro-intestinal cancers radiotherapy: the ultimate aim of the research of my...
Tumour Radiosensitivity Research Group
Our research focuses on finding new ways of making tumours more sensitive to radiotherapy...
Chromosome Integrity Group
The aim or our research is to understand how genome stability is maintained in response to DNA...
Adjuvant Colorectal Cancer Group
Delivering the right treatment to the right patient at the right time.
DNA Repair in Cancer Treatment Group
We are investigating DNA damage signalling and repair factors in bladder cancer to develop new...
Cancer Cell Cycle Group
Research in Nick La Thangue’s group focusses on the mechanisms that give rise to the abnormal...
IGF Group
We are studying the role of insulin-like growth factor (IGF) signalling in tumour biology,...
Clinical Research Programmes, CRUK/MRC Oxford Institute for Radiation Oncology
We aim to deliver a step change in the effectiveness of radiotherapy through the evaluation of...
DNA Damage and Repair Group
We aim to understand how repair of damaged DNA is controlled during chromosome duplication, and...
Director, CRUK/MRC Oxford Institute for Radiation Oncology. Molecular Resistance to Treatments Group
Our research links basic science with clinical applications and focuses on understanding the...
Head of Department of Oncology. Early Phase Clinical Trials & Melanoma Therapy
Mark Middleton’s research concentrates on development of new cancer drugs and on the treatment...
Mechanisms of Metastasis Group
We are interested in the mechanisms underlying the development of metastasis, the spread of...
My interests over the years have focussed on the chemistry and biochemical pathways involved in...
Cell Signalling Group
Our research aims to understand the cell and molecular biology behind frequent tumour mutations...
DNA Damage Response Group
We are interested in the role of the ubiquitin-proteasome system in DNA repair, ageing, cancer...
Lung Cancer Research Group
Our group aims to identify novel therapies that target subgroups of lung cancer patients...
Oxford Molecular Diagnostics Centre
The aim of our research is to identify molecular-based disease classifiers using clinical omics...
Anticancer Viruses and Cancer Vaccines Group
The aim of our research is to design and develop innovative cancer killing viruses and oncolytic...
Experimental Neuroimaging Group
Our goals are to identify the role of the inflammatory and metabolic microenvironment in brain...
Genome Stability and Tumourigenesis Group
Our research is focused on gaining a greater understanding of how homologous recombination (HR...
The Radiotherapeutics and Radioimaging Group
Personalising radiotherapy using functional imaging: we apply functional and molecular imaging...
Radiation Therapy Medical Physics Group
Our research group specialises in bringing fundamental physical concepts to enhance everyday...
Advanced Technology Development Group
Our work focuses on the application of novel imaging modalities and on the development of...
Core Facilities
Graham Brown, Core Leader
The Bioanalysis Core provides support in flow cytometry and in measuring concentrations of small...
Francesca Buffa, Academic Lead
We provide expertise in computational biology ranging from applied statistics to computational...
Frank Van den Heuvel, Academic Lead
The Clinical Radiotherapy Core supports the implementation of clinical trials involving novel...
Sandie Wellman, Core Leader
The Early Phase Clinical Trials Unit aims to support the translation of research findings in to...
Sarah Blagden, Academic Lead
The goal of the Oxford Experimental Cancer Medicine (ECMC) GCP laboratories is to accelerate the...
Sean Smart, Core Leader
The Imaging Core provides routine technical support services and operates a programme of...
John Prentice, Workshop Manager
The Mechanical Workshop assists numerous scientific groups within the Department and the...
Rhodri Wilson, Core Leader
The Microscopy Core aims to provide research groups with imaging technologies to investigate...
Sarah Pearson, Trial Management Director
The Oncology Clinical Trials Office (OCTO) provides clinical trial management support to...
Rebekka Hueting, Core Leader
The PET Radiochemistry and Radiopharmacy core supports radiochemistry-dependent research...
Mark Hill, Core Leader
The Radiation Biophysics Core facilitates radiation research within the department and...
About Us
We aim to enhance clinical and basic cancer research in Oxford with the ultimate goal of increasing cancer cure rates.
Research
In Oxford, we have a great wealth of broad-ranging expertise and a powerful network of cancer researchers.
Study With Us
Our graduate training programmes for both scientists and clinicians are internationally recognised.