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DPhil (PhD) Programme

The Department of Oncology offers to science graduates and clinical research fellows the opportunity to undertake doctoral research leading to a Doctor of Philosophy (PhD) degree via two courses 1) DPhil in Oncology or 2) DPhil in Radiation Oncology. Applicants choose from a list of DPhil projects placed on offer every year by prospective supervisors.

The DPhil in Oncology programme of study offers up to four-years of study with subject areas covering the entire spectrum of oncology.

The DPhil in Radiation Oncology (1+3) is a four-year combined MSc and DPhil programme, with subject areas for the three-year DPhil portion covering the spectrum of oncology relevant to the treatment of cancer by radiotherapy and its underlying biological mechanisms.

DPhil projects for 2019 entry

The list of DPhil projects on offer for October 2019 entry is detailed below:

A Gastrointestinal Epithelial Organoid Assay to Identify Non-Toxic Chemoradiation Combinations for Cancer Treatment
Supervisors: Anne Kiltie, Anderson Ryan
 
A STING in the Tail for Cancer
Supervisors: Peter McHugh, Adrian L Harris.
 
Characterisation of DNA-protein crosslink proteolysis repair
Supervisors: Kristijan Ramadan, Benedikt Kessler.
 
Cross-presentation of exogenous ROP proteins by antigen presenting cells to MHC class I and class II pathways
 
Deciphering the regulation of non-coding RNAs in a hypoxic tumour microenvironment
Supervisors:Francesca Buffa, Adrian Harris
 
Determinants of Sensitivity to G-Quadruplex-Binding Compounds
Supervisors: Madalena Tarsounas, Anderson Ryan
 
Development of Tracers for Real-Time Endoscopic Optical Imaging for Early Detection of Oesophageal Cancer
Supervisors: Kate Vallis, Boris Vojnovic.
 
Dissecting the Determinants of Response to Checkpoint Inhibitors
Supervisors: Benjamin Fairfax, Mark Middleton.
 
Efficient homing of natural killer
 
Enhancing Radiotherapy Outcomes for Oesophageal Cancer
Supervisors: Maria Hawkins, Frank Van den Heuvel
 
Exploiting Clonal Cell Variation to Identify Novel Targets to Enhance the Effects of Radiation in Cancer Therapy
Supervisors: Anderson Ryan, Maria Hawkins
 
Hypoxia-Targeted Protein-Targeting Chimeras (htPROTACS)
Supervisors: Ester Hammond, Stuart Conway.
 
Investigating the Contribution of IGF-1 to Risk of Developing Prostate Cancer
Supervisors: Val Macaulay, Ian Mills.
 
Investigating the Potential Benefits of MRI-LINAC for Delivery of Stereotactic Ablative Radiotherapy (SBRT) in Hepatobiliary Malignancies
Supervisors: Maria Hawkins, Frank Van den Heuvel.
 
Investigating the role of Ribonucleotide Reductase (RNR) in cell physiology and cancer
Supervisors: Vincenzo D’Angiolella, Ross Chapman
 
Mathematical reconstruction of cancer networks
Supervisors: Francesca Buffa, Julio Saez-Rodriguez.
 
Molecular imaging of DNA damage repair
Supervisors: Bart Cornelissen, Nicola Sibson
 
Targeting telomere maintenance pathways in cancer
Supervisors: David Clynes, Andrew Blackford.
 
The IGF axis as a mediator of treatment resistance in glioblastoma multiforme
Supervisors: Val Macaulay, Nicola Sibson.
 
Understanding Epigenetic Control to Develop Novel Cancer Drugs
Supervisor: Nick La Thangue
 
Understanding How DNA Repair Pathway Choice is Controlled
Supervisors: Andrew Blackford, David Clynes
 
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